Abstract: A certain type of cable assembly adopts glass sintered hermetic connectors, which are assembled in the first working procedure. The quality of the priming process directly affects the final product qualification rate. At present, this process is fully completed manually with poor operation stability, frequent quality defects and a high product scrap rate, which greatly restricts the production schedule and on-time product delivery. To improve assembly efficiency and product yield, this paper analyzes existing quality defects and technical difficulties based on the actual production conditions of the cable assembly, and proposes schemes for designing dedicated priming tooling and process optimization. Physical trial production and on-site verification prove that the application of special priming tooling can greatly improve operating efficiency and steadily control product processing quality. The research results provide theoretical basis and practical reference for trial production and mass production of such cable assemblies, and also accumulate reliable practical data for the selection of glass sintered hermetic connectors in similar products.