Abstract: Addressing the severe ice coating on 220 kV transmission lines in cold regions, as well as the inefficiency, operational complexity, and safety risks associated with traditional de-icing methods, this paper proposes a layout and optimization design scheme for 220 kV de-icing disconnect switches. Based on the new construction project of the 500 kV Xishan Substation in Shaoyang, Hunan, and considering the layout characteristics of outdoor 220 kV HGIS distribution equipment, the study systematically investigates the configuration types and structural optimization of novel 220 kV de-icing disconnect switches. Through comparative analysis of operational time, land footprint, and safety reliability between traditional temporary jumper de-icing methods and fixed de-icing disconnect switches, along with an evaluation of the impact of different 220 kV de-icing disconnect switch layouts on project costs, a universal de-icing arrangement scheme suitable for substations in high-cold regions is proposed. The research findings demonstrate that the optimized layout of 220 kV de-icing disconnect switches can significantly improve de-icing efficiency, reduce land usage, and enhance the power grid's ice and disaster prevention capabilities, providing crucial reference for the standardization and intelligent development of de-icing technology in substations.