Abstract: In MEP installation engineering, multiple pipelines of different disciplines are often interlaced within limited spaces, where traditional methods tend to cause frequent conflicts, project delays, and resource waste. To address these challenges, this study proposes an optimization method for MEP installation engineering based on integrated pipeline layout technology. A spatial conflict risk function and a global cost model are established, and a multi-objective optimization mechanism considering space utilization, schedule coordination, and cost control is introduced. Finally, a pilot project in a distribution room is employed for validation, and the results demonstrate that the proposed method significantly reduces conflict and rework rates, shortens the construction period, and enhances resource utilization efficiency.