Abstract: In order to improve data transmission efficiency, anti-interference ability, etc., based on MIMO-OFDM application, taking natural gas field stations as an example, the design of data transmission method for industrial control network SCADA system is carried out. Taking outdoor MIMO systems under non line of sight conditions as the research object, MIMO technology is introduced, and a transmission channel model is constructed based on multiple input-output angles; using OFDM to adjust transmission power, modulation and coding parameters, introducing OFDM algorithm, and designing adaptive modulation for power allocation transmission in SCADA system; considering the special environment of high-altitude areas, introduce optical communication technology and design data transmission. The comparative experimental results show that the designed method can not only ensure the synchronization of data transmission, but also optimize data transmission efficiency on the basis of improving the anti-interference ability of data transmission.